9hmh: Difference between revisions
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==Crystal structure of the Calf domains of Integrin Alpha5== | |||
<StructureSection load='9hmh' size='340' side='right'caption='[[9hmh]], [[Resolution|resolution]] 1.92Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[9hmh]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9HMH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9HMH FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.92Å</td></tr> | |||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9hmh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9hmh OCA], [https://pdbe.org/9hmh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9hmh RCSB], [https://www.ebi.ac.uk/pdbsum/9hmh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9hmh ProSAT]</span></td></tr> | ||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/ITA5_HUMAN ITA5_HUMAN] Integrin alpha-5/beta-1 is a receptor for fibronectin and fibrinogen. It recognizes the sequence R-G-D in its ligands. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions. | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Leppanen VML]] | |||
[[Category: Murthy AV]] | |||
[[Category: Ponna SK]] | |||
[[Category: Saharinen PI]] | |||
[[Category: Sipila TJO]] | |||
Latest revision as of 11:36, 24 May 2026
Crystal structure of the Calf domains of Integrin Alpha5
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