9rtz: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

~~The entry~~ 9rtz is ~~ON HOLD until Paper Publication~~

==Mammalian AP3 complex on tubular membranes (ARF1 centered Delta-ARF1 dimer-Delta3 interface)==

~~Authors~~:

== Structural highlights ==

<table><tr><td colspan='2'>[[9rtz]] is a 14 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens], [https://en.wikipedia.org/wiki/Pan_troglodytes Pan troglodytes] and [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9RTZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9RTZ FirstGlance]. <br>

~~Description~~:

</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 13Å</td></tr>

[[Category: ~~Unreleased~~ Structures]]

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9rtz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9rtz OCA], [https://pdbe.org/9rtz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9rtz RCSB], [https://www.ebi.ac.uk/pdbsum/9rtz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9rtz ProSAT]</span></td></tr>

</table>

== Function ==

[https://www.uniprot.org/uniprot/A0A2I3SW12_PANTR A0A2I3SW12_PANTR] Subunit of non-clathrin- and clathrin-associated adaptor protein complex 3 (AP-3) that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. AP-3 appears to be involved in the sorting of a subset of transmembrane proteins targeted to lysosomes and lysosome-related organelles. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals.[ARBA:ARBA00023570]

__TOC__

</StructureSection>

[[Category: Homo sapiens]]

[[Category: Large Structures]]

[[Category: Pan troglodytes]]

[[Category: Rattus norvegicus]]

[[Category: Briggs JAG]]

[[Category: Kaufman JGG]]

[[Category: Owen DJ]]

[[Category: Tagiltsev G]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 9rtz is ON HOLD  until Paper Publication
+==Mammalian AP3 complex on tubular membranes (ARF1 centered Delta-ARF1 dimer-Delta3 interface)==
+<StructureSection load='9rtz' size='340' side='right'caption='[[9rtz]], [[Resolution|resolution]] 13.00&Aring;' scene=''>
-Authors:
+== Structural highlights ==
+<table><tr><td colspan='2'>[[9rtz]] is a 14 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens], [https://en.wikipedia.org/wiki/Pan_troglodytes Pan troglodytes] and [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9RTZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9RTZ FirstGlance]. <br>
-Description:
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 13&#8491;</td></tr>
-[[Category: Unreleased Structures]]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9rtz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9rtz OCA], [https://pdbe.org/9rtz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9rtz RCSB], [https://www.ebi.ac.uk/pdbsum/9rtz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9rtz ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/A0A2I3SW12_PANTR A0A2I3SW12_PANTR] Subunit of non-clathrin- and clathrin-associated adaptor protein complex 3 (AP-3) that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. AP-3 appears to be involved in the sorting of a subset of transmembrane proteins targeted to lysosomes and lysosome-related organelles. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals.[ARBA:ARBA00023570]
+__TOC__
+</StructureSection>
+[[Category: Homo sapiens]]
+[[Category: Large Structures]]
+[[Category: Pan troglodytes]]
+[[Category: Rattus norvegicus]]
+[[Category: Briggs JAG]]
+[[Category: Kaufman JGG]]
+[[Category: Owen DJ]]
+[[Category: Tagiltsev G]]