9rty: Difference between revisions
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==Mammalian AP3 complex on tubular membranes (ARF1 centered Beta3-ARF1 dimer-Delta interface)== | |||
<StructureSection load='9rty' size='340' side='right'caption='[[9rty]], [[Resolution|resolution]] 8.90Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[9rty]] is a 14 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens], [https://en.wikipedia.org/wiki/Pan_troglodytes Pan troglodytes] and [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9RTY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9RTY FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 8.9Å</td></tr> | |||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9rty FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9rty OCA], [https://pdbe.org/9rty PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9rty RCSB], [https://www.ebi.ac.uk/pdbsum/9rty PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9rty ProSAT]</span></td></tr> | ||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/A0A8V8TQW4_HUMAN A0A8V8TQW4_HUMAN] Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. Involved in process of CD8+ T-cell and NK cell degranulation. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals.[ARBA:ARBA00055970] | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Pan troglodytes]] | |||
[[Category: Rattus norvegicus]] | |||
[[Category: Briggs JAG]] | |||
[[Category: Kaufman JGG]] | |||
[[Category: Owen DJ]] | |||
[[Category: Tagiltsev G]] | |||
Latest revision as of 04:59, 27 May 2026
Mammalian AP3 complex on tubular membranes (ARF1 centered Beta3-ARF1 dimer-Delta interface)
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