10yo: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

~~The entry~~ 10yo is ~~ON HOLD until Paper Publication~~

==Nocardia pseudobrasiliensis DnaA DI==

~~Authors~~:

== Structural highlights ==

<table><tr><td colspan='2'>[[10yo]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Nocardia Nocardia]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=10YO OCA]. For a guided tour on the structure components use [https://proteopedia.org/fgij/fg.htm?mol=10YO FirstGlance].

~~Description~~:

</td></tr><tr id='method'><td class="sblockLbl">[[Empirical_models|Method:]]</td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8Å</td></tr>

[[Category: ~~Unreleased~~ Structures]]

<tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[https://proteopedia.org/fgij/fg.htm?mol=10yo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=10yo OCA], [https://pdbe.org/10yo PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=10yo RCSB], [https://www.ebi.ac.uk/pdbsum/10yo PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=10yo ProSAT]</td></tr>

</table>

== Function ==

[https://www.uniprot.org/uniprot/A0A370HTC5_9NOCA A0A370HTC5_9NOCA] Plays an essential role in the initiation and regulation of chromosomal replication. ATP-DnaA binds to the origin of replication (oriC) to initiate formation of the DNA replication initiation complex once per cell cycle. Binds the DnaA box (a 9 base pair repeat at the origin) and separates the double-stranded (ds)DNA. Forms a right-handed helical filament on oriC DNA; dsDNA binds to the exterior of the filament while single-stranded (ss)DNA is stabiized in the filament's interior. The ATP-DnaA-oriC complex binds and stabilizes one strand of the AT-rich DNA unwinding element (DUE), permitting loading of DNA polymerase. After initiation quickly degrades to an ADP-DnaA complex that is not apt for DNA replication. Binds acidic phospholipids.[HAMAP-Rule:MF_00377][RuleBase:RU000577]

__TOC__

</StructureSection>

[[Category: Large Structures]]

[[Category: Nocardia]]

[[Category: Chavez Orozco JG]]

[[Category: Ellis PK]]

[[Category: Schumacher MA]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 10yo is ON HOLD  until Paper Publication
+==Nocardia pseudobrasiliensis DnaA DI==
+<StructureSection load='10yo' size='340' side='right'caption='[[10yo]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
-Authors:
+== Structural highlights ==
+<table><tr><td colspan='2'>[[10yo]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Nocardia Nocardia]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=10YO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=10YO FirstGlance]. <br>
-Description:
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
-[[Category: Unreleased Structures]]
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=10yo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=10yo OCA], [https://pdbe.org/10yo PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=10yo RCSB], [https://www.ebi.ac.uk/pdbsum/10yo PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=10yo ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/A0A370HTC5_9NOCA A0A370HTC5_9NOCA] Plays an essential role in the initiation and regulation of chromosomal replication. ATP-DnaA binds to the origin of replication (oriC) to initiate formation of the DNA replication initiation complex once per cell cycle. Binds the DnaA box (a 9 base pair repeat at the origin) and separates the double-stranded (ds)DNA. Forms a right-handed helical filament on oriC DNA; dsDNA binds to the exterior of the filament while single-stranded (ss)DNA is stabiized in the filament's interior. The ATP-DnaA-oriC complex binds and stabilizes one strand of the AT-rich DNA unwinding element (DUE), permitting loading of DNA polymerase. After initiation quickly degrades to an ADP-DnaA complex that is not apt for DNA replication. Binds acidic phospholipids.[HAMAP-Rule:MF_00377][RuleBase:RU000577]
+__TOC__
+</StructureSection>
+[[Category: Large Structures]]
+[[Category: Nocardia]]
+[[Category: Chavez Orozco JG]]
+[[Category: Ellis PK]]
+[[Category: Schumacher MA]]