9rxb: Difference between revisions

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'''Unreleased structure'''


The entry 9rxb is ON HOLD  until Paper Publication
==VPS34-CII (VPS34/VPS15/BECLIN1/UVRAG) bound to RAB5A (Q79L) on the VPS34 and VPS15 subunits==
 
<StructureSection load='9rxb' size='340' side='right'caption='[[9rxb]], [[Resolution|resolution]] 4.03&Aring;' scene=''>
Authors: Spokaite, S., Ohashi, Y., Dessus, A.N., Bourguet, M., Williams, R.L.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[9rxb]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9RXB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9RXB FirstGlance]. <br>
Description: VPS34-CII (VPS34/VPS15/BECLIN1/UVRAG) bound to RAB5A (Q79L) on the VPS34 and VPS15 subunits
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 4.03&#8491;</td></tr>
[[Category: Unreleased Structures]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=GTP:GUANOSINE-5-TRIPHOSPHATE'>GTP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=MYR:MYRISTIC+ACID'>MYR</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
[[Category: Williams, R.L]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9rxb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9rxb OCA], [https://pdbe.org/9rxb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9rxb RCSB], [https://www.ebi.ac.uk/pdbsum/9rxb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9rxb ProSAT]</span></td></tr>
[[Category: Spokaite, S]]
</table>
[[Category: Ohashi, Y]]
== Function ==
[[Category: Bourguet, M]]
[https://www.uniprot.org/uniprot/PK3C3_HUMAN PK3C3_HUMAN] Catalytic subunit of the PI3K complex that mediates formation of phosphatidylinositol 3-phosphate which plays a key role in initiation and maturation of autophagosomes. Involved in the transport of lysosomal enzyme precursors to lysosomes. Required for the abcission step in cytokinesis. Required for transport from early to late endosomes.<ref>PMID:7628435</ref> <ref>PMID:14617358</ref> <ref>PMID:20208530</ref>
[[Category: Dessus, A.N]]
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Bourguet M]]
[[Category: Dessus AN]]
[[Category: Ohashi Y]]
[[Category: Spokaite S]]
[[Category: Williams RL]]
Retrieved from "https://proteopedia.org/9rxb"