9vm2: Difference between revisions
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The entry | ==Structure of DOCK6-Cdc42 complex protomer== | ||
<StructureSection load='9vm2' size='340' side='right'caption='[[9vm2]], [[Resolution|resolution]] 3.94Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[9vm2]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9VM2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9VM2 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.94Å</td></tr> | |||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9vm2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9vm2 OCA], [https://pdbe.org/9vm2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9vm2 RCSB], [https://www.ebi.ac.uk/pdbsum/9vm2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9vm2 ProSAT]</span></td></tr> | ||
</table> | |||
== Disease == | |||
[https://www.uniprot.org/uniprot/DOCK6_HUMAN DOCK6_HUMAN] Adams-Oliver syndrome. The disease is caused by variants affecting the gene represented in this entry. | |||
== Function == | |||
[https://www.uniprot.org/uniprot/DOCK6_HUMAN DOCK6_HUMAN] Acts as a guanine nucleotide exchange factor (GEF) for CDC42 and RAC1 small GTPases. Through its activation of CDC42 and RAC1, may regulate neurite outgrowth (By similarity).<ref>PMID:17196961</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Hanada K]] | |||
[[Category: Ishizuka-Katsura Y]] | |||
[[Category: Katsura K]] | |||
[[Category: Kukimoto-Niino M]] | |||
[[Category: Shirouzu M]] | |||
[[Category: Yonemochi M]] | |||
Latest revision as of 06:56, 3 June 2026
Structure of DOCK6-Cdc42 complex protomer
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