9w0o: Difference between revisions

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'''Unreleased structure'''


The entry 9w0o is ON HOLD  until Paper Publication
==cryoEM structure of S1P3 in complex with heterotrimeric G protein==
 
<StructureSection load='9w0o' size='340' side='right'caption='[[9w0o]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
Authors: Wu, B., Zhao, Q., Tan, Q.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[9w0o]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9W0O OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9W0O FirstGlance]. <br>
Description: cryoEM structure of S1P3 in complex with heterotrimeric G protein
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3&#8491;</td></tr>
[[Category: Unreleased Structures]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9w0o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9w0o OCA], [https://pdbe.org/9w0o PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9w0o RCSB], [https://www.ebi.ac.uk/pdbsum/9w0o PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9w0o ProSAT]</span></td></tr>
[[Category: Tan, Q]]
</table>
[[Category: Wu, B]]
== Function ==
[[Category: Zhao, Q]]
[https://www.uniprot.org/uniprot/GNAI1_HUMAN GNAI1_HUMAN] Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(i) proteins are involved in hormonal regulation of adenylate cyclase: they inhibit the cyclase in response to beta-adrenergic stimuli. The inactive GDP-bound form prevents the association of RGS14 with centrosomes and is required for the translocation of RGS14 from the cytoplasm to the plasma membrane. May play a role in cell division.<ref>PMID:17635935</ref> <ref>PMID:17264214</ref>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Tan Q]]
[[Category: Wu B]]
[[Category: Zhao Q]]
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