10ri: Difference between revisions

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'''Unreleased structure'''


The entry 10ri is ON HOLD  until Paper Publication
==Dimeric complex of VEGF, VEGFR2 and Neuropilin 1==
 
<StructureSection load='10ri' size='340' side='right'caption='[[10ri]], [[Resolution|resolution]] 3.60&Aring;' scene=''>
Authors:  
== Structural highlights ==
 
<table><tr><td colspan='2'>[[10ri]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=10RI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=10RI FirstGlance]. <br>
Description:  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.6&#8491;</td></tr>
[[Category: Unreleased Structures]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=10ri FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=10ri OCA], [https://pdbe.org/10ri PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=10ri RCSB], [https://www.ebi.ac.uk/pdbsum/10ri PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=10ri ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/NRP1_MOUSE NRP1_MOUSE] Receptor involved in the development of the cardiovascular system, in angiogenesis, in the formation of certain neuronal circuits and in organogenesis outside the nervous system. It mediates the chemorepulsant activity of semaphorins. It binds to semaphorin 3A, the PLGF-2 isoform of PGF, the VEGF-165 isoform of VEGF and VEGF-B. Coexpression with KDR results in increased VEGF-165 binding to KDR as well as increased chemotaxis. It may regulate VEGF-induced angiogenesis (By similarity).
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Bai X]]
[[Category: Chen L]]
[[Category: Zhang X]]
Retrieved from "https://proteopedia.org/10ri"