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'''Unreleased structure'''


The entry 9kvs is ON HOLD  until 2027-06-05
==Structure of SB290157 bound to human C3aR in complex with Go (Receptor Ligand Focused map)==
 
<StructureSection load='9kvs' size='340' side='right'caption='[[9kvs]], [[Resolution|resolution]] 2.81&Aring;' scene=''>
Authors: Banerjee, R., Sano, F.K., Yadav, M.K., Sawada, K., Ganguly, M., Mishra, S., Dalal, A., Nureki, O., Shukla, A.K.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[9kvs]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9KVS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9KVS FirstGlance]. <br>
Description: Structure of SB290157 bound to human C3aR in complex with Go (Receptor Ligand Focused map)
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.81&#8491;</td></tr>
[[Category: Unreleased Structures]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A1L6Y:(2~{S})-5-[bis(azanyl)methylideneamino]-2-[2-(2,2-diphenylethoxy)ethanoylamino]pentanoic+acid'>A1L6Y</scene></td></tr>
[[Category: Sawada, K]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9kvs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9kvs OCA], [https://pdbe.org/9kvs PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9kvs RCSB], [https://www.ebi.ac.uk/pdbsum/9kvs PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9kvs ProSAT]</span></td></tr>
[[Category: Sano, F.K]]
</table>
[[Category: Mishra, S]]
== Function ==
[[Category: Nureki, O]]
[https://www.uniprot.org/uniprot/ACM4_HUMAN ACM4_HUMAN] The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is inhibition of adenylate cyclase.[https://www.uniprot.org/uniprot/C3AR_HUMAN C3AR_HUMAN] Receptor for the chemotactic and inflammatory peptide anaphylatoxin C3a. This receptor stimulates chemotaxis, granule enzyme release and superoxide anion production.
[[Category: Banerjee, R]]
__TOC__
[[Category: Dalal, A]]
</StructureSection>
[[Category: Ganguly, M]]
[[Category: Homo sapiens]]
[[Category: Shukla, A.K]]
[[Category: Large Structures]]
[[Category: Yadav, M.K]]
[[Category: Banerjee R]]
[[Category: Dalal A]]
[[Category: Ganguly M]]
[[Category: Mishra S]]
[[Category: Nureki O]]
[[Category: Sano FK]]
[[Category: Sawada K]]
[[Category: Shukla AK]]
[[Category: Yadav MK]]
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