9ori: Difference between revisions
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==Crystal structure of clinically relevant H117Y mutant of AGR2== | |||
<StructureSection load='9ori' size='340' side='right'caption='[[9ori]], [[Resolution|resolution]] 1.74Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[9ori]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9ORI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9ORI FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.74Å</td></tr> | |||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9ori FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9ori OCA], [https://pdbe.org/9ori PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9ori RCSB], [https://www.ebi.ac.uk/pdbsum/9ori PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9ori ProSAT]</span></td></tr> | ||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/AGR2_HUMAN AGR2_HUMAN] Required for MUC2 post-transcriptional synthesis and secretion. May play a role in the production of mucus by intestinal cells (By similarity). Proto-oncogene that may play a role in cell migration, cell differentiation and cell growth.<ref>PMID:18199544</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Redinbo MR]] | |||
[[Category: Walton WG]] | |||
Latest revision as of 15:04, 10 June 2026
Crystal structure of clinically relevant H117Y mutant of AGR2
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