9owv: Difference between revisions
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==Structure of Geobacillus stearothermophilus RNase P holoenzyme in complex with mature tRNA in 5 mM Ca2+== | |||
<StructureSection load='9owv' size='340' side='right'caption='[[9owv]], [[Resolution|resolution]] 3.02Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[9owv]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Geobacillus_stearothermophilus Geobacillus stearothermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9OWV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9OWV FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.02Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9owv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9owv OCA], [https://pdbe.org/9owv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9owv RCSB], [https://www.ebi.ac.uk/pdbsum/9owv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9owv ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/A0A150N245_GEOSE A0A150N245_GEOSE] RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.[ARBA:ARBA00002663][HAMAP-Rule:MF_00227] | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Geobacillus stearothermophilus]] | |||
[[Category: Large Structures]] | |||
[[Category: Lee Y-T]] | |||
[[Category: Stagno JR]] | |||
[[Category: Wang Y-X]] | |||
Latest revision as of 15:04, 10 June 2026
Structure of Geobacillus stearothermophilus RNase P holoenzyme in complex with mature tRNA in 5 mM Ca2+
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