9v9w: Difference between revisions

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'''Unreleased structure'''


The entry 9v9w is ON HOLD  until Paper Publication
==Cryo-EM structure of the ncPRC1.4 complex containing two RYBP bound to the H2AK119ub-modified nucleosome==
 
<StructureSection load='9v9w' size='340' side='right'caption='[[9v9w]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
Authors:  
== Structural highlights ==
 
<table><tr><td colspan='2'>[[9v9w]] is a 14 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Xenopus_laevis Xenopus laevis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9V9W OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9V9W FirstGlance]. <br>
Description:  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3&#8491;</td></tr>
[[Category: Unreleased Structures]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9v9w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9v9w OCA], [https://pdbe.org/9v9w PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9v9w RCSB], [https://www.ebi.ac.uk/pdbsum/9v9w PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9v9w ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/RYBP_HUMAN RYBP_HUMAN] Inhibits ubiquitination and subsequent degradation of TP53, and thereby plays a role in regulating transcription of TP53 target genes. May be implicated in the regulation of the transcription as a repressor of the transcriptional activity of E4TF1. May bind to DNA. Promotes apoptosis.<ref>PMID:11395500</ref> <ref>PMID:11953439</ref> <ref>PMID:14765135</ref> <ref>PMID:19098711</ref>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Xenopus laevis]]
[[Category: Cai D]]
[[Category: Huang J]]
[[Category: Yu Y]]
[[Category: Zhang YZ]]
Retrieved from "https://proteopedia.org/9v9w"