9zb5: Difference between revisions
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==Cryo-EM structure of the parainfluenza virus hemagglutinin-neuraminidase protein in complex with the human antibodies PIV3HN-05 and PIV3HN-13== | |||
<StructureSection load='9zb5' size='340' side='right'caption='[[9zb5]], [[Resolution|resolution]] 3.29Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[9zb5]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Human_respirovirus_3 Human respirovirus 3]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9ZB5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9ZB5 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.29Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr> | ||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9zb5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9zb5 OCA], [https://pdbe.org/9zb5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9zb5 RCSB], [https://www.ebi.ac.uk/pdbsum/9zb5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9zb5 ProSAT]</span></td></tr> | ||
[[Category: Mousa | </table> | ||
== Function == | |||
[https://www.uniprot.org/uniprot/Q81080_PI3H4 Q81080_PI3H4] Attaches the virus to sialic acid-containing cell receptors and thereby initiating infection. Binding of HN protein to the receptor induces a conformational change that allows the F protein to trigger virion/cell membranes fusion.[ARBA:ARBA00025476] | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Human respirovirus 3]] | |||
[[Category: Large Structures]] | |||
[[Category: McCaffrey KD]] | |||
[[Category: Mousa JJ]] | |||
Latest revision as of 15:23, 10 June 2026
Cryo-EM structure of the parainfluenza virus hemagglutinin-neuraminidase protein in complex with the human antibodies PIV3HN-05 and PIV3HN-13
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