9hk7: Difference between revisions
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==Crystal structure of IMPDH from Burkholderia thailandensis== | |||
<StructureSection load='9hk7' size='340' side='right'caption='[[9hk7]], [[Resolution|resolution]] 1.78Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[9hk7]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Burkholderia_thailandensis Burkholderia thailandensis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9HK7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9HK7 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.78Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=GTP:GUANOSINE-5-TRIPHOSPHATE'>GTP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | ||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9hk7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9hk7 OCA], [https://pdbe.org/9hk7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9hk7 RCSB], [https://www.ebi.ac.uk/pdbsum/9hk7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9hk7 ProSAT]</span></td></tr> | ||
[[Category: | </table> | ||
[[Category: | == Function == | ||
[[Category: Labesse | [https://www.uniprot.org/uniprot/Q2SWW9_BURTA Q2SWW9_BURTA] Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.[HAMAP-Rule:MF_01964] | ||
[[Category: | __TOC__ | ||
</StructureSection> | |||
[[Category: Burkholderia thailandensis]] | |||
[[Category: Large Structures]] | |||
[[Category: Ayoub N]] | |||
[[Category: Gelin M]] | |||
[[Category: Haouz A]] | |||
[[Category: Labesse G]] | |||
[[Category: Munier-Lehmann H]] | |||
Latest revision as of 07:07, 17 June 2026
Crystal structure of IMPDH from Burkholderia thailandensis
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