9rdo: Difference between revisions

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'''Unreleased structure'''


The entry 9rdo is ON HOLD  until 2027-06-03
==SUDV VP40 in complex with 4-Fluoro-2-hydroxybenzamide==
 
<StructureSection load='9rdo' size='340' side='right'caption='[[9rdo]], [[Resolution|resolution]] 1.65&Aring;' scene=''>
Authors: Werner, A.-D., Laube, L., Diederich, W., Becker, S.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[9rdo]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Sudan_ebolavirus Sudan ebolavirus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9RDO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9RDO FirstGlance]. <br>
Description: SUDV VP40 in complex with 4-Fluoro-2-hydroxybenzamide
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.65&#8491;</td></tr>
[[Category: Unreleased Structures]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=OGL:4-fluoranyl-2-oxidanyl-benzamide'>OGL</scene></td></tr>
[[Category: Becker, S]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9rdo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9rdo OCA], [https://pdbe.org/9rdo PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9rdo RCSB], [https://www.ebi.ac.uk/pdbsum/9rdo PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9rdo ProSAT]</span></td></tr>
[[Category: Diederich, W]]
</table>
[[Category: Laube, L]]
== Function ==
[[Category: Werner, A.-D]]
[https://www.uniprot.org/uniprot/VP40_EBOSU VP40_EBOSU] Promotes virus assembly and budding by interacting with host proteins of the multivesicular body pathway. May facilitate virus budding by interacting with the nucleocapsid and the plasma membrane. Specific interactions with membrane-associated GP and VP24 during the budding process may also occur. The hexamer form seems to be involved in budding. The octamer form binds RNA, and may play a role in genome replication (By similarity).
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Sudan ebolavirus]]
[[Category: Becker S]]
[[Category: Diederich W]]
[[Category: Laube L]]
[[Category: Werner A-D]]

Latest revision as of 07:16, 17 June 2026

SUDV VP40 in complex with 4-Fluoro-2-hydroxybenzamide

9rdo, resolution 1.65Å

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