9w2g: Difference between revisions
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==Cryo-EM structure of EB1001-bound neurokinin 2 receptor (NK2R) in complex with miniGs/q70== | |||
<StructureSection load='9w2g' size='340' side='right'caption='[[9w2g]], [[Resolution|resolution]] 3.40Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[9w2g]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens], [https://en.wikipedia.org/wiki/Lama_glama Lama glama] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9W2G OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9W2G FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.4Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MLE:N-METHYLLEUCINE'>MLE</scene>, <scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene>, <scene name='pdbligand=NLE:NORLEUCINE'>NLE</scene></td></tr> | ||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9w2g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9w2g OCA], [https://pdbe.org/9w2g PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9w2g RCSB], [https://www.ebi.ac.uk/pdbsum/9w2g PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9w2g ProSAT]</span></td></tr> | ||
[[Category: Gerhart-Hines | </table> | ||
[[Category: Pavlovskyil | == Function == | ||
[[Category: Ren | [https://www.uniprot.org/uniprot/GBB1_HUMAN GBB1_HUMAN] Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.<ref>PMID:18611381</ref> | ||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Lama glama]] | |||
[[Category: Large Structures]] | |||
[[Category: Synthetic construct]] | |||
[[Category: Gerhart-Hines Z]] | |||
[[Category: Liu X]] | |||
[[Category: Pavlovskyil A]] | |||
[[Category: Ren Y]] | |||
Latest revision as of 07:24, 17 June 2026
Cryo-EM structure of EB1001-bound neurokinin 2 receptor (NK2R) in complex with miniGs/q70
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