9wgb: Difference between revisions
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==Cryo-EM structure of I3L-ssDNA double-ring complex== | |||
<StructureSection load='9wgb' size='340' side='right'caption='[[9wgb]], [[Resolution|resolution]] 3.60Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[9wgb]] is a 16 chain structure with sequence from [https://en.wikipedia.org/wiki/Monkeypox_virus_Zaire-96-I-16 Monkeypox virus Zaire-96-I-16]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9WGB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9WGB FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.6Å</td></tr> | |||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9wgb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9wgb OCA], [https://pdbe.org/9wgb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9wgb RCSB], [https://www.ebi.ac.uk/pdbsum/9wgb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9wgb ProSAT]</span></td></tr> | ||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/Q8V516_MONPZ Q8V516_MONPZ] Plays an essential role in viral DNA replication. Binds to ssDNA with high affinity and localizes to cytoplasmic factories where nascent viral genomes accumulate. May disrupt loops, hairpins and other secondary structures present on ssDNA to reduce and eliminate pausing of viral DNA polymerase at specific sites during elongation.[ARBA:ARBA00034682] | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Monkeypox virus Zaire-96-I-16]] | |||
[[Category: Ma J]] | |||
[[Category: Yang K]] | |||
Latest revision as of 07:26, 17 June 2026
Cryo-EM structure of I3L-ssDNA double-ring complex
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