1y8d: Difference between revisions

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[[Image:1y8d.gif|left|200px]]
[[Image:1y8d.gif|left|200px]]


{{Structure
<!--
|PDB= 1y8d |SIZE=350|CAPTION= <scene name='initialview01'>1y8d</scene>
The line below this paragraph, containing "STRUCTURE_1y8d", creates the "Structure Box" on the page.
|SITE=
You may change the PDB parameter (which sets the PDB file loaded into the applet)
|LIGAND= <scene name='pdbligand=DA:2&#39;-DEOXYADENOSINE-5&#39;-MONOPHOSPHATE'>DA</scene>, <scene name='pdbligand=DG:2&#39;-DEOXYGUANOSINE-5&#39;-MONOPHOSPHATE'>DG</scene>, <scene name='pdbligand=DT:THYMIDINE-5&#39;-MONOPHOSPHATE'>DT</scene>
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|ACTIVITY=
or leave the SCENE parameter empty for the default display.
|GENE=
-->
|DOMAIN=
{{STRUCTURE_1y8d|  PDB=1y8d |  SCENE= }}  
|RELATEDENTRY=[[1eeg|1EEG]], [[1jjp|1JJP]]
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1y8d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1y8d OCA], [http://www.ebi.ac.uk/pdbsum/1y8d PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1y8d RCSB]</span>
}}


'''Dimeric parallel-stranded tetraplex with 3+1 5' G-tetrad interface, single-residue chain reversal loops and GAG triad in the context of A(GGGG) pentad'''
'''Dimeric parallel-stranded tetraplex with 3+1 5' G-tetrad interface, single-residue chain reversal loops and GAG triad in the context of A(GGGG) pentad'''
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==About this Structure==
==About this Structure==
1Y8D is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/ ]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Y8D OCA].  
Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Y8D OCA].  


==Reference==
==Reference==
An interlocked dimeric parallel-stranded DNA quadruplex: a potent inhibitor of HIV-1 integrase., Phan AT, Kuryavyi V, Ma JB, Faure A, Andreola ML, Patel DJ, Proc Natl Acad Sci U S A. 2005 Jan 18;102(3):634-9. Epub 2005 Jan 6. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15637158 15637158]
An interlocked dimeric parallel-stranded DNA quadruplex: a potent inhibitor of HIV-1 integrase., Phan AT, Kuryavyi V, Ma JB, Faure A, Andreola ML, Patel DJ, Proc Natl Acad Sci U S A. 2005 Jan 18;102(3):634-9. Epub 2005 Jan 6. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15637158 15637158]
[[Category: Protein complex]]
[[Category: Andreola, M L.]]
[[Category: Andreola, M L.]]
[[Category: Faure, A.]]
[[Category: Faure, A.]]
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[[Category: Patel, D J.]]
[[Category: Patel, D J.]]
[[Category: Phan, A T.]]
[[Category: Phan, A T.]]
[[Category: (a)gggg pentad]]
[[Category: 3+1 g-tetrad]]
[[Category: 3+1 g-tetrad]]
[[Category: dimeric parallel-stranded quadruplex]]
[[Category: Dimeric parallel-stranded quadruplex]]
[[Category: dna aptamer;hiv-1 integrase inhibitor design]]
[[Category: Dna aptamer;hiv-1 integrase inhibitor design]]
[[Category: gag triad]]
[[Category: Gag triad]]
[[Category: single nucleotide chain reversal loop]]
[[Category: Single nucleotide chain reversal loop]]
 
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