9l38: Difference between revisions
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==Structure of ENBT1 in the apo state== | |||
<StructureSection load='9l38' size='340' side='right'caption='[[9l38]], [[Resolution|resolution]] 3.20Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[9l38]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9L38 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9L38 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.2Å</td></tr> | |||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9l38 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9l38 OCA], [https://pdbe.org/9l38 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9l38 RCSB], [https://www.ebi.ac.uk/pdbsum/9l38 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9l38 ProSAT]</span></td></tr> | ||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/S43A3_HUMAN S43A3_HUMAN] Sodium-independent purine-selective nucleobase transporter which mediates the equilibrative transport of extracellular purine nucleobases such as adenine, guanine and hypoxanthine (PubMed:26455426, PubMed:32339528). May regulate fatty acid (FA) transport in adipocytes, acting as a positive regulator of FA efflux and as a negative regulator of FA uptake (By similarity).[UniProtKB:A2AVZ9]<ref>PMID:26455426</ref> <ref>PMID:32339528</ref> Sodium-independent purine-selective nucleobase transporter which mediates the equilibrative transport of extracellular purine nucleobase adenine (PubMed:30910793). Mediates the influx and efflux of the purine nucleobase analog drug 6-mercaptopurine across the membrane (PubMed:30910793).<ref>PMID:30910793</ref> Sodium-independent purine-selective nucleobase transporter which mediates the equilibrative transport of extracellular purine nucleobase adenine (PubMed:30910793). Mediates the influx and efflux of the purine nucleobase analog drug 6-mercaptopurine across the membrane (PubMed:30910793).<ref>PMID:30910793</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Ding D]] | |||
[[Category: Lu YS]] | |||
[[Category: Yin YX]] | |||
Latest revision as of 04:35, 24 June 2026
Structure of ENBT1 in the apo state
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