9s3f: Difference between revisions
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==Cryo-EM structure of Gephyrin in complex with Darpin 27F3, revealing linker-E domain interactions== | |||
<StructureSection load='9s3f' size='340' side='right'caption='[[9s3f]], [[Resolution|resolution]] 3.12Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[9s3f]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9S3F OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9S3F FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.12Å</td></tr> | |||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9s3f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9s3f OCA], [https://pdbe.org/9s3f PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9s3f RCSB], [https://www.ebi.ac.uk/pdbsum/9s3f PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9s3f ProSAT]</span></td></tr> | ||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/GEPH_RAT GEPH_RAT] Microtubule-associated protein involved in membrane protein-cytoskeleton interactions. It is thought to anchor the inhibitory glycine receptor (GLYR) to subsynaptic microtubules (By similarity). Catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released.<ref>PMID:8264797</ref> <ref>PMID:9990024</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Rattus norvegicus]] | |||
[[Category: Synthetic construct]] | |||
[[Category: Boettcher B]] | |||
[[Category: Hove T]] | |||
[[Category: Ortiz-Lopez D]] | |||
[[Category: Schindelin H]] | |||
Latest revision as of 04:50, 24 June 2026
Cryo-EM structure of Gephyrin in complex with Darpin 27F3, revealing linker-E domain interactions
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