23so: Difference between revisions
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==Cryo-EM structure of the cebranopadol-mu opioid receptor-Gi complex== | |||
<StructureSection load='23so' size='340' side='right'caption='[[23so]], [[Resolution|resolution]] 2.95Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[23so]] is a 7 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus], [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens], [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=23SO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=23SO FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.95Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A1E5L:6-fluoranyl-~{N},~{N}-dimethyl-1-phenyl-spiro[4,9-dihydro-3~{H}-pyrano[3,4-b]indole-1,4-cyclohexane]-1-amine'>A1E5L</scene>, <scene name='pdbligand=CLR:CHOLESTEROL'>CLR</scene></td></tr> | ||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=23so FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=23so OCA], [https://pdbe.org/23so PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=23so RCSB], [https://www.ebi.ac.uk/pdbsum/23so PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=23so ProSAT]</span></td></tr> | ||
[[Category: | </table> | ||
[[Category: Hu | == Function == | ||
[[Category: Shen | [https://www.uniprot.org/uniprot/GBB1_RAT GBB1_RAT] Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. | ||
[[Category: | __TOC__ | ||
[[Category: | </StructureSection> | ||
[[Category: Bos taurus]] | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Rattus norvegicus]] | |||
[[Category: Synthetic construct]] | |||
[[Category: Hu W]] | |||
[[Category: Huang X]] | |||
[[Category: Lai Y]] | |||
[[Category: Shen S]] | |||
[[Category: Wang Y]] | |||
[[Category: Xu HE]] | |||
Latest revision as of 12:40, 1 July 2026
Cryo-EM structure of the cebranopadol-mu opioid receptor-Gi complex
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