9pro: Difference between revisions
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==Human 19S proteasome bound to TXNL1 PITH domain and PSMD5== | |||
<StructureSection load='9pro' size='340' side='right'caption='[[9pro]], [[Resolution|resolution]] 4.07Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[9pro]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9PRO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9PRO FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 4.07Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=AGS:PHOSPHOTHIOPHOSPHORIC+ACID-ADENYLATE+ESTER'>AGS</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9pro FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9pro OCA], [https://pdbe.org/9pro PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9pro RCSB], [https://www.ebi.ac.uk/pdbsum/9pro PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9pro ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/PRS7_HUMAN PRS7_HUMAN] The 26S protease is involved in the ATP-dependent degradation of ubiquitinated proteins. The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex. In case of HIV-1 infection, positive modulator of Tat-mediated transactivation.<ref>PMID:9295362</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Chen X]] | |||
[[Category: Negi H]] | |||
[[Category: Walters KJ]] | |||
Latest revision as of 12:49, 1 July 2026
Human 19S proteasome bound to TXNL1 PITH domain and PSMD5
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