13gh: Difference between revisions
From Proteopedia
Jump to navigationJump to search
m Protected "13gh": Seeded page ([Edit=Allow only administrators] (indefinite) [Move=Allow only administrators] (indefinite)) |
No edit summary |
||
| Line 1: | Line 1: | ||
==IST1 bound to PI(3,5)P2 containing membrane== | |||
<StructureSection load='13gh' size='340' side='right'caption='[[13gh]], [[Resolution|resolution]] 2.56Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[13gh]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=13GH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=13GH FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.56Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EUJ:(2R)-3-{[(S)-hydroxy{[(1S,2R,3R,4S,5S,6R)-2,4,6-trihydroxy-3,5-bis(phosphonooxy)cyclohexyl]oxy}phosphoryl]oxy}propane-1,2-diyl+dioctanoate'>EUJ</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=13gh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=13gh OCA], [https://pdbe.org/13gh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=13gh RCSB], [https://www.ebi.ac.uk/pdbsum/13gh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=13gh ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/IST1_HUMAN IST1_HUMAN] Proposed to be involved in specific functions of the ESCRT machinery. Is required for efficient abscission during cytokinesis, but not for HIV-1 budding. The involvement in the MVB pathway is not established. Involved in recruiting VPS4A and/or VPS4B to the midbody of dividing cells.<ref>PMID:19129479</ref> <ref>PMID:19129480</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Alian A]] | |||
[[Category: Frost A]] | |||
[[Category: McCullough J]] | |||
[[Category: Moss III FR]] | |||
[[Category: Sundquist WI]] | |||
[[Category: Talledge N]] | |||
Revision as of 07:16, 8 July 2026
IST1 bound to PI(3,5)P2 containing membrane
| ||||||||||||
