36cg: Difference between revisions
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Created page with "'''Unreleased structure''' The entry 36cg is ON HOLD Authors: Wang, L., How, W.T. Description: Apo form of human bile salts export pump ABCB11 Category: Unreleased Structures Category: How, W.T Category: Wang, L" |
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==Apo form of human bile salts export pump ABCB11== | |||
<StructureSection load='36cg' size='340' side='right'caption='[[36cg]], [[Resolution|resolution]] 3.50Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[36cg]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=36CG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=36CG FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.5Å</td></tr> | |||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=36cg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=36cg OCA], [https://pdbe.org/36cg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=36cg RCSB], [https://www.ebi.ac.uk/pdbsum/36cg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=36cg ProSAT]</span></td></tr> | ||
[[Category: How | </table> | ||
[[Category: Wang | == Disease == | ||
[https://www.uniprot.org/uniprot/ABCBB_HUMAN ABCBB_HUMAN] Progressive familial intrahepatic cholestasis type 2;Intrahepatic cholestasis of pregnancy;Benign recurrent intrahepatic cholestasis type 2. The disease is caused by mutations affecting the gene represented in this entry. The disease is caused by mutations affecting the gene represented in this entry. | |||
== Function == | |||
[https://www.uniprot.org/uniprot/ABCBB_HUMAN ABCBB_HUMAN] Catalyzes the secretion of conjugated bile salts across the canalicular membrane of hepatocytes in an ATP-dependent manner (PubMed:16332456). Transports taurine-conjugated bile salts more rapidly than glycine-conjugated bile salts (PubMed:16332456).<ref>PMID:16332456</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: How WT]] | |||
[[Category: Wang L]] | |||
Revision as of 07:19, 8 July 2026
Apo form of human bile salts export pump ABCB11
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