9vuh: Difference between revisions
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==CDK11B ternary complex bound to AT7519== | |||
<StructureSection load='9vuh' size='340' side='right'caption='[[9vuh]], [[Resolution|resolution]] 2.70Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[9vuh]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9VUH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9VUH FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.7Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=LZE:4-{[(2,6-DICHLOROPHENYL)CARBONYL]AMINO}-N-PIPERIDIN-4-YL-1H-PYRAZOLE-3-CARBOXAMIDE'>LZE</scene>, <scene name='pdbligand=SEP:PHOSPHOSERINE'>SEP</scene>, <scene name='pdbligand=TPO:PHOSPHOTHREONINE'>TPO</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9vuh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9vuh OCA], [https://pdbe.org/9vuh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9vuh RCSB], [https://www.ebi.ac.uk/pdbsum/9vuh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9vuh ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/CD11B_HUMAN CD11B_HUMAN] Plays multiple roles in cell cycle progression, cytokinesis and apoptosis. Involved in pre-mRNA splicing in a kinase activity-dependent manner. Isoform 7 may act as a negative regulator of normal cell cycle progression.<ref>PMID:12501247</ref> <ref>PMID:12624090</ref> <ref>PMID:18216018</ref> <ref>PMID:2217177</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Shi Y]] | |||
[[Category: Wang L]] | |||
[[Category: Yang Y]] | |||
[[Category: Zhan X]] | |||
[[Category: Zheng Z]] | |||