10sj: Difference between revisions
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==20S Alpha 3 Deletion proteasome core particle in complex with Blm10== | |||
<StructureSection load='10sj' size='340' side='right'caption='[[10sj]], [[Resolution|resolution]] 3.70Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[10sj]] is a 22 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=10SJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=10SJ FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.7Å</td></tr> | |||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=10sj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=10sj OCA], [https://pdbe.org/10sj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=10sj RCSB], [https://www.ebi.ac.uk/pdbsum/10sj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=10sj ProSAT]</span></td></tr> | ||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/PSB6_YEAST PSB6_YEAST] The proteasome degrades poly-ubiquitinated proteins in the cytoplasm and in the nucleus. It is essential for the regulated turnover of proteins and for the removal of misfolded proteins. The proteasome is a multicatalytic proteinase complex that is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. It has an ATP-dependent proteolytic activity. | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Saccharomyces cerevisiae S288C]] | |||
[[Category: Fermin Perez E]] | |||
[[Category: Hanna J]] | |||
[[Category: Rawson S]] | |||
[[Category: Venclovaite U]] | |||
[[Category: Walsh Jr RM]] | |||
Latest revision as of 16:00, 22 July 2026
20S Alpha 3 Deletion proteasome core particle in complex with Blm10
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