9pnc: Difference between revisions
From Proteopedia
Jump to navigationJump to search
No edit summary |
No edit summary |
||
| Line 1: | Line 1: | ||
==Crystal structure of human mitochondrial ClpP protease C144R mutant in complex with imipridone compound, TR-65== | |||
<StructureSection load='9pnc' size='340' side='right'caption='[[9pnc]], [[Resolution|resolution]] 2.70Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[9pnc]] is a 14 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9PNC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9PNC FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PJF:3-[[7-[(4-chlorophenyl)methyl]-8-oxidanylidene-2,5,7,11-tetrazatricyclo[7.4.0.0^{2,6}]trideca-1(9),5-dien-11-yl]methyl]benzenecarbonitrile'>PJF</scene></td></tr> | ||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9pnc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9pnc OCA], [https://pdbe.org/9pnc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9pnc RCSB], [https://www.ebi.ac.uk/pdbsum/9pnc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9pnc ProSAT]</span></td></tr> | ||
[[Category: | </table> | ||
== Function == | |||
[https://www.uniprot.org/uniprot/CLPP_HUMAN CLPP_HUMAN] Clp cleaves peptides in various proteins in a process that requires ATP hydrolysis. Clp may be responsible for a fairly general and central housekeeping function rather than for the degradation of specific substrates. | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Houry WA]] | |||
[[Category: Mabanglo MF]] | |||
Latest revision as of 16:13, 22 July 2026
Crystal structure of human mitochondrial ClpP protease C144R mutant in complex with imipridone compound, TR-65
| ||||||||||||
