29vy: Difference between revisions
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==Structure of Tetrahydrocannabinolic acid synthase(THCAS) in complex with FAD== | |||
<StructureSection load='29vy' size='340' side='right'caption='[[29vy]], [[Resolution|resolution]] 2.33Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[29vy]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Cannabis_sativa Cannabis sativa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=29VY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=29VY FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.33Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=29vy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=29vy OCA], [https://pdbe.org/29vy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=29vy RCSB], [https://www.ebi.ac.uk/pdbsum/29vy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=29vy ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/THCAS_CANSA THCAS_CANSA] Catalyzes the oxidative cyclization of the monoterpene moiety in cannabigerolic acid (CBGA), producing delta(9)-tetrahydrocannabinolate (THCA), the major cannabioid in drug-type Cannabis plants. Can also use cannabinerolic acid as substrate, but not cannabigerol or cannabinerol.<ref>PMID:15190053</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Cannabis sativa]] | |||
[[Category: Large Structures]] | |||
[[Category: Cartwright J]] | |||
[[Category: Domenech J]] | |||
[[Category: Grogan G]] | |||
Latest revision as of 19:56, 29 July 2026
Structure of Tetrahydrocannabinolic acid synthase(THCAS) in complex with FAD
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