31ho: Difference between revisions
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==Crystal structure of tau tubulin kinase 1 (TTBK1) in complex with compound 62== | |||
<StructureSection load='31ho' size='340' side='right'caption='[[31ho]], [[Resolution|resolution]] 2.70Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[31ho]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=31HO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=31HO FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A1J95:~{N}-[4-(furan-2-yl)phenyl]-7~{H}-pyrrolo[2,3-d]pyrimidin-4-amine'>A1J95</scene></td></tr> | ||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=31ho FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=31ho OCA], [https://pdbe.org/31ho PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=31ho RCSB], [https://www.ebi.ac.uk/pdbsum/31ho PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=31ho ProSAT]</span></td></tr> | ||
[[Category: | </table> | ||
[[Category: | == Function == | ||
[[Category: Sanchez-Santos | [https://www.uniprot.org/uniprot/TTBK1_HUMAN TTBK1_HUMAN] Serine/threonine kinase which is able to phosphorylate TAU on serine, threonine and tyrosine residues. Induces aggregation of TAU.<ref>PMID:16923168</ref> | ||
[[Category: | == References == | ||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Knapp S]] | |||
[[Category: Martinez A]] | |||
[[Category: Sanchez-Santos C]] | |||
[[Category: Zhubi R]] | |||
Latest revision as of 19:57, 29 July 2026
Crystal structure of tau tubulin kinase 1 (TTBK1) in complex with compound 62
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