9thk: Difference between revisions
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The entry | ==Structure of human CLN8 in an apo-state== | ||
<StructureSection load='9thk' size='340' side='right'caption='[[9thk]], [[Resolution|resolution]] 3.60Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[9thk]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9THK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9THK FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.6Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=COA:COENZYME+A'>COA</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9thk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9thk OCA], [https://pdbe.org/9thk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9thk RCSB], [https://www.ebi.ac.uk/pdbsum/9thk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9thk ProSAT]</span></td></tr> | |||
</table> | |||
== Disease == | |||
[https://www.uniprot.org/uniprot/CLN8_HUMAN CLN8_HUMAN] Late infantile CLN8 disease;Northern epilepsy. The disease is caused by variants affecting the gene represented in this entry. The disease is caused by variants affecting the gene represented in this entry. | |||
== Function == | |||
[https://www.uniprot.org/uniprot/CLN8_HUMAN CLN8_HUMAN] Could play a role in cell proliferation during neuronal differentiation and in protection against cell death.<ref>PMID:19431184</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Lacabanne D]] | |||
[[Category: Petkevicius K]] | |||
[[Category: Ruprecht JJ]] | |||
[[Category: Sheokand PK]] | |||
Latest revision as of 20:24, 29 July 2026
Structure of human CLN8 in an apo-state
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