9wdd: Difference between revisions

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'''Unreleased structure'''


The entry 9wdd is ON HOLD  until 2027-08-19
==Crystal structure of NAMPT-KPT-7523 complex==
 
<StructureSection load='9wdd' size='340' side='right'caption='[[9wdd]], [[Resolution|resolution]] 1.45&Aring;' scene=''>
Authors: Lee, S.J., Park, J.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[9wdd]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9WDD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9WDD FirstGlance]. <br>
Description: Crystal structure of NAMPT-KPT-7523 complex
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.45&#8491;</td></tr>
[[Category: Unreleased Structures]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A1MBG:(~{E})-3-(6-azanylpyridin-3-yl)-~{N}-[[(2~{S})-7-chloranyl-5-(4-piperazin-1-ylcarbonylphenyl)-2,3-dihydro-1-benzofuran-2-yl]methyl]prop-2-enamide'>A1MBG</scene></td></tr>
[[Category: Lee, S.J]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9wdd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9wdd OCA], [https://pdbe.org/9wdd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9wdd RCSB], [https://www.ebi.ac.uk/pdbsum/9wdd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9wdd ProSAT]</span></td></tr>
[[Category: Park, J]]
</table>
== Function ==
[https://www.uniprot.org/uniprot/NAMPT_HUMAN NAMPT_HUMAN] Catalyzes the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, an intermediate in the biosynthesis of NAD. It is the rate limiting component in the mammalian NAD biosynthesis pathway (By similarity).
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Lee SJ]]
[[Category: Park J]]
Retrieved from "https://proteopedia.org/9wdd"