9y9d: Difference between revisions
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The entry | ==Cryo-EM structure of wild-type human CNNM4 tetramer with Magnesium and MgATP in outward-facing state== | ||
<StructureSection load='9y9d' size='340' side='right'caption='[[9y9d]], [[Resolution|resolution]] 3.48Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[9y9d]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9Y9D OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9Y9D FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.48Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9y9d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9y9d OCA], [https://pdbe.org/9y9d PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9y9d RCSB], [https://www.ebi.ac.uk/pdbsum/9y9d PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9y9d ProSAT]</span></td></tr> | |||
</table> | |||
== Disease == | |||
[https://www.uniprot.org/uniprot/CNNM4_HUMAN CNNM4_HUMAN] Jalili syndrome. The disease is caused by mutations affecting the gene represented in this entry. | |||
== Function == | |||
[https://www.uniprot.org/uniprot/CNNM4_HUMAN CNNM4_HUMAN] Probable metal transporter. The interaction with the metal ion chaperone COX11 suggests that it may play a role in sensory neuron functions (By similarity). May play a role in biomineralization and retinal function.<ref>PMID:19200527</ref> <ref>PMID:19200525</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Bai Z]] | |||
[[Category: Du J]] | |||
[[Category: Lu W]] | |||
[[Category: Zhou E]] | |||
Latest revision as of 20:33, 29 July 2026
Cryo-EM structure of wild-type human CNNM4 tetramer with Magnesium and MgATP in outward-facing state
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