36xs: Difference between revisions
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==Structure of MBD4 R512K/D560N on a T:G Mispair== | |||
<StructureSection load='36xs' size='340' side='right'caption='[[36xs]], [[Resolution|resolution]] 1.57Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[36xs]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=36XS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=36XS FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.57Å</td></tr> | |||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=36xs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=36xs OCA], [https://pdbe.org/36xs PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=36xs RCSB], [https://www.ebi.ac.uk/pdbsum/36xs PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=36xs ProSAT]</span></td></tr> | ||
[[Category: Barnes | </table> | ||
[[Category: Lee | == Function == | ||
[https://www.uniprot.org/uniprot/MBD4_HUMAN MBD4_HUMAN] Mismatch-specific DNA N-glycosylase involved in DNA repair. Has thymine glycosylase activity and is specific for G:T mismatches within methylated and unmethylated CpG sites. Can also remove uracil or 5-fluorouracil in G:U mismatches. Has no lyase activity. Was first identified as methyl-CpG-binding protein.<ref>PMID:10097147</ref> <ref>PMID:10930409</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Synthetic construct]] | |||
[[Category: Barnes R]] | |||
[[Category: Lee S]] | |||
Latest revision as of 07:10, 5 August 2026
Structure of MBD4 R512K/D560N on a T:G Mispair
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