2g9c: Difference between revisions
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2g9c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2g9c OCA], [https://pdbe.org/2g9c PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2g9c RCSB], [https://www.ebi.ac.uk/pdbsum/2g9c PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2g9c ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2g9c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2g9c OCA], [https://pdbe.org/2g9c PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2g9c RCSB], [https://www.ebi.ac.uk/pdbsum/2g9c PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2g9c ProSAT]</span></td></tr> | ||
</table> | </table> | ||
<div style="background-color:#fffaf0;"> | |||
== Publication Abstract from PubMed == | |||
The purine riboswitch is a genetic regulatory element found in the 5'-untranslated regions of Gram-positive bacteria that regulates expression of the mRNA specifically in response to either guanine or adenine. We report that the adenine-responsive RNA element is also capable of specifically recognizing pyrimidine compounds bearing modifications at the 6- or 5,6-positions in a fashion similar to that of purine compounds. Using isothermal titration calorimetry and X-ray crystallography, the binding of these compounds is characterized. | |||
Modified pyrimidines specifically bind the purine riboswitch.,Gilbert SD, Mediatore SJ, Batey RT J Am Chem Soc. 2006 Nov 8;128(44):14214-5. PMID:17076468<ref>PMID:17076468</ref> | |||
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | |||
</div> | |||
<div class="pdbe-citations 2g9c" style="background-color:#fffaf0;"></div> | |||
==See Also== | ==See Also== | ||
*[[Riboswitch 3D structures|Riboswitch 3D structures]] | *[[Riboswitch 3D structures|Riboswitch 3D structures]] | ||
== References == | |||
<references/> | |||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
Latest revision as of 08:06, 13 August 2026
Modified pyrimidines Specifically bind the purine riboswitch
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