3qf8: Difference between revisions
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3qf8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3qf8 OCA], [https://pdbe.org/3qf8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3qf8 RCSB], [https://www.ebi.ac.uk/pdbsum/3qf8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3qf8 ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3qf8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3qf8 OCA], [https://pdbe.org/3qf8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3qf8 RCSB], [https://www.ebi.ac.uk/pdbsum/3qf8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3qf8 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
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== Publication Abstract from PubMed == | |||
We describe a crystal structure, at atomic resolution (1.1 A, 100 K), of a ruthenium polypyridyl complex bound to duplex DNA, in which one ligand acts as a wedge in the minor groove, resulting in the 51 degrees kinking of the double helix. The complex cation Lambda-[Ru(1,4,5,8-tetraazaphenanthrene)(2)(dipyridophenazine)](2+) crystallizes in a 11 ratio with the oligonucleotide d(TCGGCGCCGA) in the presence of barium ions. Each complex binds to one duplex by intercalation of the dipyridophenazine ligand and also by semiintercalation of one of the orthogonal tetraazaphenanthrene ligands into a second symmetrically equivalent duplex. The result is noncovalent cross-linking and marked kinking of DNA. | |||
Structure determination of an intercalating ruthenium dipyridophenazine complex which kinks DNA by semiintercalation of a tetraazaphenanthrene ligand.,Hall JP, O'Sullivan K, Naseer A, Smith JA, Kelly JM, Cardin CJ Proc Natl Acad Sci U S A. 2011 Oct 3. PMID:21969542<ref>PMID:21969542</ref> | |||
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | |||
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<div class="pdbe-citations 3qf8" style="background-color:#fffaf0;"></div> | |||
== References == | |||
<references/> | |||
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</StructureSection> | </StructureSection> | ||
Latest revision as of 10:06, 13 August 2026
X-ray crystal structure of the ruthenium complex [Ru(tap)2(dppz)]2+ bound to d(TCGGCGCCGA) at medium resolution
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