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<StructureSection load='7kem' size='340' side='right'caption='[[7kem]], [[Resolution|resolution]] 1.77&Aring;' scene=''>
<StructureSection load='7kem' size='340' side='right'caption='[[7kem]], [[Resolution|resolution]] 1.77&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[7kem]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7KEM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7KEM FirstGlance]. <br>
<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7KEM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7KEM FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.77&#8491;</td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.77&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=0JC:DI-MU-IODOBIS(ETHYLENEDIAMINE)DIPLATINUM(II)'>0JC</scene>, <scene name='pdbligand=6CL:6-CARBOXYLYSINE'>6CL</scene>, <scene name='pdbligand=DGL:D-GLUTAMIC+ACID'>DGL</scene>, <scene name='pdbligand=PT:PLATINUM+(II)+ION'>PT</scene></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=0JC:DI-MU-IODOBIS(ETHYLENEDIAMINE)DIPLATINUM(II)'>0JC</scene>, <scene name='pdbligand=6CL:6-CARBOXYLYSINE'>6CL</scene>, <scene name='pdbligand=DGL:D-GLUTAMIC+ACID'>DGL</scene>, <scene name='pdbligand=PT:PLATINUM+(II)+ION'>PT</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7kem FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7kem OCA], [https://pdbe.org/7kem PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7kem RCSB], [https://www.ebi.ac.uk/pdbsum/7kem PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7kem ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7kem FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7kem OCA], [https://pdbe.org/7kem PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7kem RCSB], [https://www.ebi.ac.uk/pdbsum/7kem PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7kem ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/LDT2_MYCTU LDT2_MYCTU] Generates 3->3 cross-links in peptidoglycan, catalyzing the cleavage of the mDap(3)-D-Ala(4) bond of a tetrapeptide donor stem and the formation of a bond between the carbonyl of mDap(3) of the donor stem and the side chain of mDap(3) of the acceptor stem. Is specific for donor substrates containing a stem tetrapeptide since it cannot use pentapeptide stems.<ref>PMID:24041897</ref>
== References ==
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Mycobacterium tuberculosis H37Rv]]
[[Category: Dias MVB]]
[[Category: Dias MVB]]
[[Category: Libreros GA]]
[[Category: Libreros GA]]

Latest revision as of 14:23, 13 August 2026

Crystallographic structure of L,D-transpeptidase 2 from Mycobacterium tuberculosis

7kem, resolution 1.77Å

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