10ry: Difference between revisions
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==Crystal structure of compound 8t bound to PaLpxC== | |||
<StructureSection load='10ry' size='340' side='right'caption='[[10ry]], [[Resolution|resolution]] 1.90Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[10ry]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=10RY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=10RY FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.902Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A1C8O:1-{(2S)-3-(5-hydroxy-6-oxo-1,6-dihydropyrimidin-4-yl)-2-[4-({4-[(morpholin-4-yl)methyl]phenyl}ethynyl)phenyl]propyl}azetidine-3-carbonitrile'>A1C8O</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | ||
[[Category: Martin | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=10ry FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=10ry OCA], [https://pdbe.org/10ry PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=10ry RCSB], [https://www.ebi.ac.uk/pdbsum/10ry PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=10ry ProSAT]</span></td></tr> | ||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/LPXC_PSEA8 LPXC_PSEA8] Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis. | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Pseudomonas aeruginosa]] | |||
[[Category: Martin DP]] | |||