9xj8: Difference between revisions

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'''Unreleased structure'''


The entry 9xj8 is ON HOLD  until Paper Publication
==Cryo-EM structure of Hsp90(E47A)-FKBP8 complex==
 
<StructureSection load='9xj8' size='340' side='right'caption='[[9xj8]], [[Resolution|resolution]] 4.09&Aring;' scene=''>
Authors:  
== Structural highlights ==
 
<table><tr><td colspan='2'>[[9xj8]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9XJ8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9XJ8 FirstGlance]. <br>
Description:  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 4.09&#8491;</td></tr>
[[Category: Unreleased Structures]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9xj8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9xj8 OCA], [https://pdbe.org/9xj8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9xj8 RCSB], [https://www.ebi.ac.uk/pdbsum/9xj8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9xj8 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/HS90A_HUMAN HS90A_HUMAN] Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function.<ref>PMID:15937123</ref> <ref>PMID:11274138</ref>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Bai Z]]
[[Category: Ge M]]
[[Category: Li Z]]
[[Category: Zhang Y]]
[[Category: Zhang Z]]