10pq: Difference between revisions
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==Crystal structure of bovine ALDH3A1 H290L mutant - apo form== | |||
<StructureSection load='10pq' size='340' side='right'caption='[[10pq]], [[Resolution|resolution]] 1.40Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[10pq]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=10PQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=10PQ FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.4Å</td></tr> | |||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=10pq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=10pq OCA], [https://pdbe.org/10pq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=10pq RCSB], [https://www.ebi.ac.uk/pdbsum/10pq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=10pq ProSAT]</span></td></tr> | ||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/F1N015_BOVIN F1N015_BOVIN] ALDHs play a major role in the detoxification of alcohol-derived acetaldehyde. They are involved in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation. Oxidizes medium and long chain aldehydes into non-toxic fatty acids. Preferentially oxidizes aromatic aldehyde substrates. Comprises about 50 percent of corneal epithelial soluble proteins. May play a role in preventing corneal damage caused by ultraviolet light.[ARBA:ARBA00045468] | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Bos taurus]] | |||
[[Category: Large Structures]] | |||
[[Category: Hsu N]] | |||
[[Category: Kim J]] | |||
[[Category: Li H]] | |||
[[Category: Qiao F]] | |||
[[Category: Saleh S]] | |||
Latest revision as of 16:36, 8 September 2026
Crystal structure of bovine ALDH3A1 H290L mutant - apo form
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