9wgh: Difference between revisions
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==Solution structure of human VAPB MSP domain== | |||
<StructureSection load='9wgh' size='340' side='right'caption='[[9wgh]]' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[9wgh]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9WGH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9WGH FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR, models</td></tr> | |||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9wgh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9wgh OCA], [https://pdbe.org/9wgh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9wgh RCSB], [https://www.ebi.ac.uk/pdbsum/9wgh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9wgh ProSAT]</span></td></tr> | ||
[[Category: | </table> | ||
[[Category: | == Disease == | ||
[[Category: Fujiwara | [https://www.uniprot.org/uniprot/VAPB_HUMAN VAPB_HUMAN] Adult-onset proximal spinal muscular atrophy, autosomal dominant;Amyotrophic lateral sclerosis. The disease is caused by mutations affecting the gene represented in this entry. The disease is caused by mutations affecting the gene represented in this entry. | ||
[[Category: | == Function == | ||
[[Category: | [https://www.uniprot.org/uniprot/VAPB_HUMAN VAPB_HUMAN] Participates in the endoplasmic reticulum unfolded protein response (UPR) by inducing ERN1/IRE1 activity. Involved in cellular calcium homeostasis regulation.<ref>PMID:16891305</ref> <ref>PMID:20940299</ref> <ref>PMID:22131369</ref> | ||
[[Category: | == References == | ||
[[Category: | <references/> | ||
[[Category: Komuro | __TOC__ | ||
[[Category: | </StructureSection> | ||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Enomoto-Kusano M]] | |||
[[Category: Fujiwara T]] | |||
[[Category: Furuita K]] | |||
[[Category: Kobayashi N]] | |||
[[Category: Kodama ST]] | |||
[[Category: Kojima C]] | |||
[[Category: Komuro R]] | |||
[[Category: Miyanoiri Y]] | |||
[[Category: Togawa W]] | |||
Latest revision as of 16:53, 8 September 2026
Solution structure of human VAPB MSP domain
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