22jx: Difference between revisions
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==Cryo-EM structure of the mGlu5-beta-arrestin 1 complex== | |||
<StructureSection load='22jx' size='340' side='right'caption='[[22jx]], [[Resolution|resolution]] 3.70Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[22jx]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=22JX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=22JX FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.7Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GLU:GLUTAMIC+ACID'>GLU</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=SEP:PHOSPHOSERINE'>SEP</scene>, <scene name='pdbligand=TPO:PHOSPHOTHREONINE'>TPO</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=22jx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=22jx OCA], [https://pdbe.org/22jx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=22jx RCSB], [https://www.ebi.ac.uk/pdbsum/22jx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=22jx ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/GRM5_HUMAN GRM5_HUMAN] Receptor for glutamate. The activity of this receptor is mediated by a G-protein that activates a phosphatidylinositol-calcium second messenger system and generates a calcium-activated chloride current. | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Mus musculus]] | |||
[[Category: Chen K]] | |||
[[Category: Chu X]] | |||
[[Category: Feng Y]] | |||
[[Category: Han S]] | |||
[[Category: Lin S]] | |||
[[Category: Ma L]] | |||
[[Category: Wang Z]] | |||
[[Category: Wei J]] | |||
[[Category: Wu B]] | |||
[[Category: Yi C]] | |||
[[Category: Zhang C]] | |||
[[Category: Zhao Q]] | |||
Latest revision as of 07:53, 9 September 2026
Cryo-EM structure of the mGlu5-beta-arrestin 1 complex
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