9wkr: Difference between revisions
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==structure of human propionyl-coenzyme A carboxylase in BC binding state== | |||
<StructureSection load='9wkr' size='340' side='right'caption='[[9wkr]], [[Resolution|resolution]] 3.53Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[9wkr]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9WKR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9WKR FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.53Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BTI:5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL'>BTI</scene></td></tr> | ||
[[Category: Su | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9wkr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9wkr OCA], [https://pdbe.org/9wkr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9wkr RCSB], [https://www.ebi.ac.uk/pdbsum/9wkr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9wkr ProSAT]</span></td></tr> | ||
[[Category: Tian | </table> | ||
== Disease == | |||
[https://www.uniprot.org/uniprot/PCCA_HUMAN PCCA_HUMAN] Defects in PCCA are the cause of propionic acidemia type I (PA-1) [MIM:[https://omim.org/entry/606054 606054]. PA-1 is a life-threatening disease characterized by episodic vomiting, lethargy and ketosis, neutropenia, periodic thrombocytopenia, hypogammaglobulinemia, developmental retardation, and intolerance to protein.<ref>PMID:10101253</ref> <ref>PMID:12559849</ref> <ref>PMID:15059621</ref> <ref>PMID:10329019</ref> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/PCCA_HUMAN PCCA_HUMAN] | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Su JY]] | |||
[[Category: Tian XY]] | |||
Latest revision as of 08:06, 9 September 2026
structure of human propionyl-coenzyme A carboxylase in BC binding state
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