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'''Unreleased structure'''


The entry 10ih is ON HOLD  until Paper Publication
==HSV-2 gHecto/gL/53S-Fab complex==
 
<StructureSection load='10ih' size='340' side='right'caption='[[10ih]], [[Resolution|resolution]] 3.26&Aring;' scene=''>
Authors:  
== Structural highlights ==
 
<table><tr><td colspan='2'>[[10ih]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Human_herpesvirus_2_strain_HG52 Human herpesvirus 2 strain HG52] and [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=10IH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=10IH FirstGlance]. <br>
Description:  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.26&#8491;</td></tr>
[[Category: Unreleased Structures]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=10ih FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=10ih OCA], [https://pdbe.org/10ih PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=10ih RCSB], [https://www.ebi.ac.uk/pdbsum/10ih PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=10ih ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/GH_HHV2H GH_HHV2H] The heterodimer glycoprotein H-glycoprotein L is required for the fusion of viral and plasma membranes leading to virus entry into the host cell. Following initial binding of gD to one of its receptors, membrane fusion is mediated by the fusion machinery composed at least of gB and the heterodimer gH/gL. May also be involved in the fusion between the virion envelope and the outer nuclear membrane during virion morphogenesis (By similarity).
__TOC__
</StructureSection>
[[Category: Human herpesvirus 2 strain HG52]]
[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Gonzalez-Del Pino GL]]
[[Category: Heldwein EE]]
[[Category: Russell HC]]
[[Category: Walsh RM]]
Retrieved from "https://proteopedia.org/10ih"