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'''Unreleased structure'''


The entry 10lh is ON HOLD  until Paper Publication
==HSV-2 gHecto/gL==
 
<StructureSection load='10lh' size='340' side='right'caption='[[10lh]], [[Resolution|resolution]] 3.71&Aring;' scene=''>
Authors: Heldwein, E.E., Gonzalez-Del Pino, G.L., Walsh, R.M.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[10lh]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Human_alphaherpesvirus_2 Human alphaherpesvirus 2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=10LH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=10LH FirstGlance]. <br>
Description: HSV-2 gHecto/gL
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.71&#8491;</td></tr>
[[Category: Unreleased Structures]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
[[Category: Gonzalez-Del Pino, G.L]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=10lh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=10lh OCA], [https://pdbe.org/10lh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=10lh RCSB], [https://www.ebi.ac.uk/pdbsum/10lh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=10lh ProSAT]</span></td></tr>
[[Category: Walsh, R.M]]
</table>
[[Category: Heldwein, E.E]]
== Function ==
[https://www.uniprot.org/uniprot/GH_HHV2H GH_HHV2H] The heterodimer glycoprotein H-glycoprotein L is required for the fusion of viral and plasma membranes leading to virus entry into the host cell. Following initial binding of gD to one of its receptors, membrane fusion is mediated by the fusion machinery composed at least of gB and the heterodimer gH/gL. May also be involved in the fusion between the virion envelope and the outer nuclear membrane during virion morphogenesis (By similarity).
__TOC__
</StructureSection>
[[Category: Human alphaherpesvirus 2]]
[[Category: Large Structures]]
[[Category: Gonzalez-Del Pino GL]]
[[Category: Heldwein EE]]
[[Category: Walsh RM]]
Retrieved from "https://proteopedia.org/10lh"