31sy: Difference between revisions

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'''Unreleased structure'''


The entry 31sy is ON HOLD  until Paper Publication
==Human wild-type LONP1 bound to PZL-26==
 
<StructureSection load='31sy' size='340' side='right'caption='[[31sy]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
Authors: Pardo-Hernandez, C., Green, J., Gustafsson, C.M.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[31sy]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=31SY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=31SY FirstGlance]. <br>
Description: Human wild-type LONP1 bound to PZL-26
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3&#8491;</td></tr>
[[Category: Unreleased Structures]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A1KDX:[(1~{R})-1-[[(2~{R})-4-morpholin-4-yl-4-oxidanylidene-2-(pyrazin-2-ylcarbonylamino)butanoyl]amino]-4-phenyl-butyl]boronic+acid'>A1KDX</scene></td></tr>
[[Category: Pardo-Hernandez, C]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=31sy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=31sy OCA], [https://pdbe.org/31sy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=31sy RCSB], [https://www.ebi.ac.uk/pdbsum/31sy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=31sy ProSAT]</span></td></tr>
[[Category: Gustafsson, C.M]]
</table>
[[Category: Green, J]]
== Function ==
[https://www.uniprot.org/uniprot/LONM_HUMAN LONM_HUMAN] ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial promoters and RNA in a single-stranded, site-specific, and strand-specific manner. May regulate mitochondrial DNA replication and/or gene expression using site-specific, single-stranded DNA binding to target the degradation of regulatory proteins binding to adjacent sites in mitochondrial promoters. Endogenous substrates include mitochondrial steroidogenic acute regulatory (StAR) protein.[HAMAP-Rule:MF_03120]<ref>PMID:12198491</ref> <ref>PMID:15870080</ref> <ref>PMID:17420247</ref> <ref>PMID:8248235</ref>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Green J]]
[[Category: Gustafsson CM]]
[[Category: Pardo-Hernandez C]]
Retrieved from "https://proteopedia.org/31sy"