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'''Unreleased structure'''


The entry 32un is ON HOLD
==Structure of ZNFX1 in the post-ATP hydrolysis state==
 
<StructureSection load='32un' size='340' side='right'caption='[[32un]], [[Resolution|resolution]] 3.20&Aring;' scene=''>
Authors:  
== Structural highlights ==
 
<table><tr><td colspan='2'>[[32un]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=32UN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=32UN FirstGlance]. <br>
Description:  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.2&#8491;</td></tr>
[[Category: Unreleased Structures]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=32un FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=32un OCA], [https://pdbe.org/32un PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=32un RCSB], [https://www.ebi.ac.uk/pdbsum/32un PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=32un ProSAT]</span></td></tr>
</table>
== Disease ==
[https://www.uniprot.org/uniprot/ZNFX1_HUMAN ZNFX1_HUMAN] The disease is caused by variants affecting the gene represented in this entry.
== Function ==
[https://www.uniprot.org/uniprot/ZNFX1_HUMAN ZNFX1_HUMAN] RNA-binding protein that initiates the antiviral response and is required to restrict the replication of RNA viruses (PubMed:33872655). Acts as a double-stranded RNA (dsRNA) sensor that recognizes viral RNA and then interacts with MAVS to initiate the type I interferon response (By similarity). Also required for immunity against some bacteria, such as mycobacteria (PubMed:33876776).[UniProtKB:Q8R151]<ref>PMID:33872655</ref> <ref>PMID:33876776</ref>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Heatley A]]
[[Category: Naydenova K]]
[[Category: Randow F]]
[[Category: Yip M]]
Retrieved from "https://proteopedia.org/32un"