9qha: Difference between revisions
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==Crystal structure of human dendritic cell immunoreceptor (DCIR) extracellular domain in complex with galactose-terminated biantennary complex-type N-glycan== | |||
<StructureSection load='9qha' size='340' side='right'caption='[[9qha]], [[Resolution|resolution]] 2.20Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[9qha]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9QHA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9QHA FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=GAL:BETA-D-GALACTOSE'>GAL</scene>, <scene name='pdbligand=GLA:ALPHA+D-GALACTOSE'>GLA</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr> | ||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9qha FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9qha OCA], [https://pdbe.org/9qha PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9qha RCSB], [https://www.ebi.ac.uk/pdbsum/9qha PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9qha ProSAT]</span></td></tr> | ||
[[Category: Rombouts | </table> | ||
[[Category: | == Function == | ||
[[Category: | [https://www.uniprot.org/uniprot/CLC4A_HUMAN CLC4A_HUMAN] May be involved in regulating immune reactivity. May play a role in modulating dendritic cells (DC) differentiation and/or maturation. May be involved via its ITIM motif (immunoreceptor tyrosine-based inhibitory motifs) in the inhibition of B-cell-receptor-mediated calcium mobilization and protein tyrosine phosphorylation.<ref>PMID:10438934</ref> | ||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Demange P]] | |||
[[Category: Rombouts Y]] | |||
[[Category: Rousset S]] | |||
[[Category: Tranier S]] | |||
Latest revision as of 09:26, 30 September 2026
Crystal structure of human dendritic cell immunoreceptor (DCIR) extracellular domain in complex with galactose-terminated biantennary complex-type N-glycan
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