9sl3: Difference between revisions

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'''Unreleased structure'''


The entry 9sl3 is ON HOLD
==Human mitoribosome bound to TACO1 (domain 1 ordered), mRNA, A/A-, P/P- and E/E-tRNAs==
 
<StructureSection load='9sl3' size='340' side='right'caption='[[9sl3]], [[Resolution|resolution]] 4.05&Aring;' scene=''>
Authors: Singh, V., Khawaja, A., Rorbach, J.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[9sl3]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9SL3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9SL3 FirstGlance]. <br>
Description: Human mitoribosome bound to TACO1 (domain 1 ordered), mRNA, A/A-, P/P-and E/E-tRNAs
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 4.05&#8491;</td></tr>
[[Category: Unreleased Structures]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1MA:6-HYDRO-1-METHYLADENOSINE-5-MONOPHOSPHATE'>1MA</scene>, <scene name='pdbligand=2MG:2N-METHYLGUANOSINE-5-MONOPHOSPHATE'>2MG</scene>, <scene name='pdbligand=5F0:(3~{S})-3-azanyl-4-methoxy-4-oxidanylidene-butanoic+acid'>5F0</scene>, <scene name='pdbligand=5MC:5-METHYLCYTIDINE-5-MONOPHOSPHATE'>5MC</scene>, <scene name='pdbligand=5MU:5-METHYLURIDINE+5-MONOPHOSPHATE'>5MU</scene>, <scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene>, <scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=B8T:[(2~{R},3~{S},4~{R},5~{R})-5-[4-(methylamino)-2-oxidanylidene-pyrimidin-1-yl]-3,4-bis(oxidanyl)oxolan-2-yl]methyl+dihydrogen+phosphate'>B8T</scene>, <scene name='pdbligand=FES:FE2/S2+(INORGANIC)+CLUSTER'>FES</scene>, <scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=MA6:6N-DIMETHYLADENOSINE-5-MONOPHOSHATE'>MA6</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>, <scene name='pdbligand=OMG:O2-METHYLGUANOSINE-5-MONOPHOSPHATE'>OMG</scene>, <scene name='pdbligand=OMU:O2-METHYLURIDINE+5-MONOPHOSPHATE'>OMU</scene>, <scene name='pdbligand=PSU:PSEUDOURIDINE-5-MONOPHOSPHATE'>PSU</scene>, <scene name='pdbligand=SPD:SPERMIDINE'>SPD</scene>, <scene name='pdbligand=THC:N-METHYLCARBONYLTHREONINE'>THC</scene>, <scene name='pdbligand=VAL:VALINE'>VAL</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
[[Category: Khawaja, A]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9sl3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9sl3 OCA], [https://pdbe.org/9sl3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9sl3 RCSB], [https://www.ebi.ac.uk/pdbsum/9sl3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9sl3 ProSAT]</span></td></tr>
[[Category: Singh, V]]
</table>
[[Category: Rorbach, J]]
== Disease ==
[https://www.uniprot.org/uniprot/TACO1_HUMAN TACO1_HUMAN] The disease is caused by variants affecting the gene represented in this entry.
== Function ==
[https://www.uniprot.org/uniprot/TACO1_HUMAN TACO1_HUMAN] Acts as a translational activator of mitochondrially-encoded cytochrome c oxidase 1.<ref>PMID:19503089</ref>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Khawaja A]]
[[Category: Rorbach J]]
[[Category: Singh V]]

Latest revision as of 09:30, 30 September 2026

Human mitoribosome bound to TACO1 (domain 1 ordered), mRNA, A/A-, P/P- and E/E-tRNAs

9sl3, resolution 4.05Å

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