9wvx: Difference between revisions
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==CryoEM structure of MRGPRX2 with peptide agonist DKD2== | |||
<StructureSection load='9wvx' size='340' side='right'caption='[[9wvx]], [[Resolution|resolution]] 2.80Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[9wvx]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9WVX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9WVX FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.8Å</td></tr> | |||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9wvx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9wvx OCA], [https://pdbe.org/9wvx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9wvx RCSB], [https://www.ebi.ac.uk/pdbsum/9wvx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9wvx ProSAT]</span></td></tr> | ||
[[Category: Fang | </table> | ||
== Disease == | |||
[https://www.uniprot.org/uniprot/DHTK1_HUMAN DHTK1_HUMAN] 2-aminoadipic 2-oxoadipic aciduria;Autosomal dominant Charcot-Marie-Tooth disease type 2Q. The disease is caused by mutations affecting the gene represented in this entry. The disease is caused by mutations affecting the gene represented in this entry. | |||
== Function == | |||
[https://www.uniprot.org/uniprot/DHTK1_HUMAN DHTK1_HUMAN] The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components: 2-oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3) (By similarity). | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Fang GX]] | |||
Latest revision as of 09:41, 30 September 2026
CryoEM structure of MRGPRX2 with peptide agonist DKD2
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