1z4u: Difference between revisions

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[[Image:1z4u.gif|left|200px]]
[[Image:1z4u.gif|left|200px]]


{{Structure
<!--
|PDB= 1z4u |SIZE=350|CAPTION= <scene name='initialview01'>1z4u</scene>, resolution 2.80&Aring;
The line below this paragraph, containing "STRUCTURE_1z4u", creates the "Structure Box" on the page.
|SITE=
You may change the PDB parameter (which sets the PDB file loaded into the applet)  
|LIGAND= <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PH9:(2Z)-2-[(1-ADAMANTYLCARBONYL)AMINO]-3-[4-(2-BROMOPHENOXY)PHENYL]PROP-2-ENOIC+ACID'>PH9</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/RNA-directed_RNA_polymerase RNA-directed RNA polymerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.48 2.7.7.48] </span>
or leave the SCENE parameter empty for the default display.
|GENE=  
-->
|DOMAIN=
{{STRUCTURE_1z4u| PDB=1z4u  | SCENE= }}  
|RELATEDENTRY=[[1yvf|1YVF]]
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1z4u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1z4u OCA], [http://www.ebi.ac.uk/pdbsum/1z4u PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1z4u RCSB]</span>
}}


'''hepatitis C virus NS5B RNA-dependent RNA polymerase complex with inhibitor PHA-00799585'''
'''hepatitis C virus NS5B RNA-dependent RNA polymerase complex with inhibitor PHA-00799585'''
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==About this Structure==
==About this Structure==
1Z4U is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Hepatitis_c_virus Hepatitis c virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Z4U OCA].  
Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Z4U OCA].  


==Reference==
==Reference==
Inhibitors of HCV NS5B polymerase. Part 2: Evaluation of the northern region of (2Z)-2-benzoylamino-3-(4-phenoxy-phenyl)-acrylic acid., Pfefferkorn JA, Nugent R, Gross RJ, Greene M, Mitchell MA, Reding MT, Funk LA, Anderson R, Wells PA, Shelly JA, Anstadt R, Finzel BC, Harris MS, Kilkuskie RE, Kopta LA, Schwende FJ, Bioorg Med Chem Lett. 2005 Jun 2;15(11):2812-8. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15911260 15911260]
Inhibitors of HCV NS5B polymerase. Part 2: Evaluation of the northern region of (2Z)-2-benzoylamino-3-(4-phenoxy-phenyl)-acrylic acid., Pfefferkorn JA, Nugent R, Gross RJ, Greene M, Mitchell MA, Reding MT, Funk LA, Anderson R, Wells PA, Shelly JA, Anstadt R, Finzel BC, Harris MS, Kilkuskie RE, Kopta LA, Schwende FJ, Bioorg Med Chem Lett. 2005 Jun 2;15(11):2812-8. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15911260 15911260]
[[Category: Hepatitis c virus]]
[[Category: Protein complex]]
[[Category: RNA-directed RNA polymerase]]
[[Category: RNA-directed RNA polymerase]]
[[Category: Anstadt, R.]]
[[Category: Anstadt, R.]]
Line 36: Line 31:
[[Category: Shelly, J A.]]
[[Category: Shelly, J A.]]
[[Category: Wells, P A.]]
[[Category: Wells, P A.]]
[[Category: finger]]
[[Category: Finger]]
[[Category: hcv]]
[[Category: Hcv]]
[[Category: ns5b]]
[[Category: Ns5b]]
[[Category: palm]]
[[Category: Palm]]
[[Category: polymerase]]
[[Category: Polymerase]]
[[Category: thumb]]
[[Category: Thumb]]
 
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Retrieved from "https://proteopedia.org/1z4u"